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Patient Story · Video · Clinical Trial

A new synthetic cartilage implant — tested in an FDA trial.

After years of debilitating knee pain, Amanda participated in an FDA trial of the Hyalex synthetic cartilage device with Dr. Gomoll — and shares how the procedure helped restore her quality of life.

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Transcript
I'm going to wear heels to my wedding. I'm going to be able to dance with my family, walk down the aisle, and I know that my knee is not going to hurt. My name's Amanda. I'm a very active person. I like to play soccer, go hiking, go running, do Pilates, and I was on a soccer league and a women's volleyball league. I first tore my ACL in 2021, and the recovery was rough, but I was able to recover from it and actually go back to playing soccer. And then, of course, a few games in, I tore the cartilage on my femur, got an OATS procedure, but unfortunately, that didn't go well either, and the pain never went away. I heard about HSS through a friend who had a good experience here. Dr. Gomoll saw my MRI from the previous surgery, which was a year and a half ago, so it should have actually been feeling a lot better, and he said that I had a lot of edema around the graft that they put in. My body didn't take it. He said that they're doing a Hyalex clinical study and that he thought that I would be a good candidate for that. Instead of a cadaver bone, it would be titanium, and the body takes really well to that. They would basically remove a piece of the femur and cartilage, and then replace it with the titanium Hyalex implant. He understood that I wanted to get back to running and soccer and sports if I could, so when he explained the Hyalex as an option, it kind of gave me a little bit of hope that maybe I could go back to sports and I wouldn't be in pain. The OATS was a very difficult recovery because my leg had to be in extension in a leg brace the entire time, and that made it really difficult to recover because the muscle atrophied so much. With the Hyalex, I did not need the brace in extension, I didn't need the brace at all, and I was able to move it and bend it the entire time. And that made physical therapy a lot easier and my recovery way faster. I was already doing 10,000 steps at 4 months, I was lunging, squatting, so I'm really excited to be able to do impact activities and running especially, and hopefully getting back to sports. And I am also getting married very soon, so I'm excited to be able to walk down the aisle with no pain and be able to dance with my family and just enjoy the time without worrying about any knee pain. I had a great experience with Dr. Gomoll and his team. They were always available to answer any questions, and he just made me feel really comfortable the entire time.

About this story

Helping advance the field — one patient at a time.

For patients with a focal cartilage defect that hasn't responded to conservative care, the standard options are osteochondral allograft transplantation, autologous chondrocyte implantation (MACI), and — in advanced cases — partial or total knee replacement. New options are continually under investigation.

The Hyalex synthetic cartilage implant is one such option, designed to replace damaged focal cartilage with a polymer material that mimics the mechanical properties of natural cartilage. As an investigational device, it's currently available only through FDA-approved clinical trials at a small number of centers.

Amanda shares her experience as a participant in that trial. For an overview of current trials Dr. Gomoll is involved in, see our clinical trials page.

About the procedure

The Hyalex Cartilage Implant

Hyalex is a new synthetic cartilage implant designed to replace damaged focal cartilage with a polymer material that mimics the mechanical properties of natural cartilage. As an investigational device, it's currently available only through FDA-approved clinical trials at a small number of centers. More on clinical trials →

Why Clinical Trials Matter

Patients like Amanda who participate in well-designed clinical trials help advance the field — making new joint-preserving options available to future patients. Dr. Gomoll's practice includes ongoing research and trials in cartilage repair and joint preservation. Learn about current trials →

Read more patient stories

Hear from more of Dr. Gomoll's patients in their own words about how they got back to the lives they love.